Balveen Kaur, Ph.D.

Associate Professor
Department of Neurological Surgery

Degree: Emory University

Contact Information
385D Wiseman Hall
400 W. 12th Avene
Columbus, OH 43210
PHONE: (614) 292-3984
FAX: (614) 688-4882
E-MAIL: Balveen.Kaur@osumc.edu

Link to NLM PubMed publications list for Balveen Kaur (last 10 years)

Research Area:

brain tumors
oncolytic virus therapy
angiogenesis
tumor microenvironment

Current Research:

To investigate changes in the tumor microenvironment associated with disease progression and in response to treatment to design better therapies. Currently active research areas include:

engineering more efficient "tumor-killing" vectors
finding and testing novel prodrug/gene therapy strategies
defining more selective oncolytic viruses
identifying biomarkers predictive of response to therapy.
defining the role of host defense response in vector delivery in tumors.

Techniques:

Animals: analysis of transgenic mice; small animal survival surgery
Cell biology: cell apoptosis assay; immunocytochemistry; immunoprecipitation; mammalian cell transfection; RNA interference; viral infection
Imaging: fluorescence and phase contrast confocal microscopy of live and fixed cells; live-animal imaging techniques; microscopic and autoradiographic image processing and analysis and three-dimensional reconstruction and visualization;
Molecular biology: cloning viral and nonviral vectors; construction of viral and nonviral expression vectors; DNA-protein interactions; ELISA; flow cytometry; FPLC; gene and microRNA arrays; in situ hybridization; Northern, Southern, and Western blotting; quantitative RT-PCR; RNA isolation; site-specific mutagenesis